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Resume of Senthil Nachimuthu E-mail
Wednesday, 11 October 2006

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PDF version (linked) last updated: November 22, 2009.
Web version (below) last updated: November 22, 2009.

 


 Senthil Kumar Nachimuthu

26S 2000E Room 5775 HSEB
Salt Lake City, UT 84112
USA

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Homepage
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http://tux.med.utah.edu/~senthil
+1 801 438 4044

A curious biomedical informaticist with experience in clinical medicine, biomedical informatics, computer science, and machine learning. Well experienced in biomedical ontologies, terminologies, semantic interoperability in healthcare, and probabilistic temporal reasoning. Interested in applying medical informatics methods to support biomedical research and improve patient care.

Present Status

 

Ph.D. Candidate in Biomedical Informatics, University of Utah School of Medicine.
Dissertation topic: "Temporal reasoning in Medicine using Dynamic Bayesian Networks".
Dissertation defense scheduled for December 2009.

Research Interests

 

Primary: Medical vocabulary, terminology and ontology standards, medical knowledge engineering, semantic interoperability, clinical decision support, temporal reasoning, patient safety.

 Secondary: Computerized clinical protocols and practice guidelines, user interface design, system architecture, natural language understanding, open source software.

Education

 

MBBS (Bachelor of Medicine and Surgery, equivalent to a United States MD degree plus a one year rotational clinical internship). June 2000. Stanley Medical College, Chennai, TN, India.
Registered as a Physician - General Practitioner with the Medical Council of India.

Professional Experience

 

 

Department of Biomedical Informatics, University of Utah, Salt Lake City, UT.

May 2004 - Now                 Graduate Assistant

n  An externally funded research project supported by 3M Health Information Systems.

n  Developing a Vocabulary Server that integrates multiple versions of several biomedical vocabularies, using a central concept-based ontology and interoperable with LexGrid and caBIG.

n  Developing heuristic search algorithms for analyzing vocabularies such as SNOMED CT, LOINC, NCI Thesaurus, ICD-9-CM, CPT, HCPCS, RxNORM, UMLS, 3M HDD, etc.

n  Developing learning algorithms for automatically mapping different vocabularies. Implementing these algorithms as Java and Web applications for remote access and portability.

n  Building and maintaining a semantic web based collaborative ontology/terminology authoring system. Designing and implementing the workflow for distributed authoring.

n  Supervising development and testing of HL7 CTS services and the vocabulary server.

n  Active role in designing the next generation interface engines, data warehouses and toolkits for data mining and analysis.

 

 

 

Department of Biomedical Informatics, University of Utah, Salt Lake City, UT.

Fall (August - December) 2006                 Teaching Assistant - Medical Decision Making

n  Taught Graduate (Masters and Ph.D.) students in the Departments of Biomedical Informatics and Nursing Informatics in the Medical Decision Making course involving decision theory, decision trees, probabilistic and Bayesian networks, neural networks and other machine learning techniques.

n  Gave invited lecture on ‘Temporal Reasoning in Medicine' involving Hidden Markov Models, Dynamic Bayesian Networks and other techniques Technology.

 

Information Technology Services, University of Utah Health Sciences Center, Salt Lake City, UT.                   

Jan 2002 - Aug 2004          Graduate Assistant.

n  Developed a patient tracking system for Cardio Thoracic Surgery, which was integrated with eChart, a home-grown web-based Electronic Medical Record system.

n  Developed a bacteremia surveillance system (rule-based clinical decision support system) for the University of Utah Epidemiology Department by analyzing HL7 data streams.

n  Evaluated methods to automatically map domestic vocabularies to UMLS.

 

Cerner Corporation, Kansas City, MO.

May - Aug 2002                 Graduate Technical Intern - Product Development.

n  Developed a research prototype for a Guideline Representation Language, Guideline Instance and a Guideline Execution Engine for web based, wizard-style implementation of Clinical Practice Guidelines

n  Performed information modeling, and created XML schemas for a prototype Guideline Representation Language

n  Developed a Guideline Execution engine in PHP utilizing XML parsers.  Developed a prototype front-end for Wizard-style guideline implementation

 

University of Utah School of Medicine, Salt Lake City, UT.              

Sep - Dec 2001                  Teaching Assistant - Human Anatomy.

n  Taught gross anatomy to the first-year medical students through cadaver dissection in the Gross Anatomy lab.

n  Taught gross anatomy with special relevance to clinical correlates.

n  Evaluated the performance of the students in written and oral exams.

 

Government Stanley Hospital, Chennai, TN, India

June 1999 to May 2000     House Officer (Rotational Internship)

n  Rotated through Internal Medicine, Pediatrics, General Surgery, Orthopedics, Trauma, Emergency, Public Health, Obstetrics and Gynecology and other departments in this 2200-bed tertiary care teaching hospital.

n  Instructed and supervised third and final year medical students and nursing students during their clinical rotations.

 

Inst. for Research and Rehabilitation of Hand; Dept. of Surgical Gastroenterology, Stanley Medical College, Chennai, TN, India.                

1999 - 2001               Consultant

n  Provided consultation to the two departments to develop a patient information system for clinical and imaging data for hand reconstructive and gastrointestinal surgeries.

 

Association for Computer Aided Surgery, Chennai, TN, India.

Sep - Oct 1999                 Pediatric Malignancies - Content Developer

n  Authored the content for Pediatric Malignancies chapter of the Pediatrics volume of an electronic learning system for medical students and clinicians, which was published on a CDROM.

 

C M Hospital, Namakkal, TN, India.

May 1994 - Jun 1996       Patient Information System Designer and Programmer.

n  Developed a patient record system in Foxbase+ on MS-DOS for this 40-bed hospital.

 

Peer-Reviewed Publications

 

n  Nachimuthu SK. Projeny: An Open Source Toolkit for Probabilistic Temporal Reasoning. AMIA Annu Symp Proc 2009. Accepted for publication.

n  He S, Nachimuthu SK, Shakib SC, Lau LM. Collaborative Authoring of Biomedical Terminologies with Semantic Wiki. AMIA Annu Symp Proc 2009. Accepted for publication.

n  Wong A, Nachimuthu SK, Haug PJ. Predicting Sepsis in the ICU using Dynamic Bayesian Networks. AMIA Annu Symp Proc 2009. Accepted for publication.

n  Nachimuthu SK. Vocabulary Metadata Service for Terminology Servers to Handle Variations in Design of Various Biomedical Terminologies. AMIA Annu Symp Proc 2008.

n  Nachimuthu SK. Best Practices for distribution of Controlled Medical Terminologies. AMIA Annu Symp Proc 2007:1055.

n  Nachimuthu SK, Lau LM. Practical Issues in Using SNOMED CT as a Reference Terminology. Proceedings of Medinfo 2007, The 12th International Health (Medical) Informatics Congress. Stud Health Technol Inform. 2007;129(Pt 1):640-4.

n  Nachimuthu SK, RD Woolstenhulme. Generalizability of Hybrid Search Algorithms to Map Multiple Biomedical Vocabulary Domains. AMIA Annu Symp Proc 2006:1042.

n  Nachimuthu SK, Lau LM. Applying Hybrid Algorithms for Text Matching to Automated Biomedical Vocabulary Mapping. AMIA Annu Symp Proc 2005:555-9.

Invited Presentations

 

n  Nachimuthu SK, Functional Overloading and Metadata Discovery to Handle Variations in Design of Various Biomedical Terminologies in HL7 CTS2. HL7 Working Group Meeting, Vancouver, Canada. September 2008.

n  Nachimuthu SK, Temporal Reasoning in Medicine. Medical Decision Making course, Department of Biomedical Informatics, University of Utah. November 2007.

n  Nachimuthu SK, Temporal Reasoning in Medicine. Medical Decision Making course, Department of Biomedical Informatics, University of Utah. October 2006.

Workshops and Tutorials

 

n  Nachimuthu SK, Smith E, Jones TM, Teichrow JS, Biondich B, Collins C, Ross W. Open Source Tools and Applications in Medical Informatics. AMIA 2007 Annual Symposium, Chicago, USA.

 

 
   

Review and Judge of Peer Research

 

n  Invited Reviewer, AMIA 2009 Annual Symposium, San Francisco, CA.

n  Invited Reviewer, AMIA 2008 Annual Symposium, Washington DC.

n  Invited Reviewer, AMIA 2007 Annual Symposium, Chicago, IL.

n  Reviewer, MedInfo 2007, 12th International Health Informatics Congress, Brisbane, Australia.

n  Reviewer, Fifth Annual Public Health Information Network Conference 2007, Atlanta, GA.

Honors and Awards

 

n  October 2009. Recipient, Graduate School Travel Assistance Award from the University of Utah to present a research abstract at the AMIA 2009 Annual Symposium, San Francisco, CA.

n  September 2007. Recipient, Graduate School Travel Assistance Award from the University of Utah to present a research paper at the MedInfo 2007 Conference, Brisbane, Australia.

n  July 2003: Represented the University of Utah Department of Biomedical Informatics in the International Master Class, International Partnership in Health Informatics Education (IPHIE), an academic collaboration between 6 universities in the US and Europe.

n  June 2000: Placed in the top 10% of the graduating class in Medical School.  Passed with First Class in 6 subjects.

n  December 1997: Placed First in Forensic Medicine and Toxicology Practical Exams, out of 168 students.

Leadership Experience

 

n  American Medical Informatics Association - Open Source Working Group (AMIA OS-WG). Chair-elect - Nov 2009 to Nov 2010. Chair - Nov 2010 to Nov 2012.

n  Indian Association for Medical Informatics - Executive Committee (IAMI EC). Elected as an Executive Committee member - Jan 2010 to Dec 2011.

Standards Development and Open Source Software

 

n  Co-author of and contributor to the HL7 Common Terminology Services 2 (CTS2) standard.

n  Author of Projeny - Probabilistic Networks Generator in Java. A probabilistic modeling toolkit developed for my PhD research. Available at http://projeny.sourceforge.net

n  Contributor of bug fixes to OpenSuse Linux distribution and other open source projects.

Computer and Programming Skills

 

Operating systems:          Linux, Windows, Mac OS
Programming:                  C, Java, XML, Visual Basic, Matlab
Design:                            Requirements analysis, SDLC analysis, UML and use-case modeling
IDE:                                Eclipse (including RCP), Visual Studio
Web development:           HTML, CSS, ColdFusion, PHP, JSP/Servlets, Javascript
Database:                         MySQL, PostgreSQL, Oracle, Microsoft Access

Other Projects

 

The Stanley Medical College Network. http://www.stanmed.net

1999 - Now                           Website Administrator and Designer

n  Maintaining the unofficial portal for the Student, Staff, Faculty and Alumni Community. Customized a PHP-based content management system.

UNICEF / Stanley Medical College, Chennai, TN, India.

1999 Dec                               Immunization Program Evaluator

n  Member of the UNICEF monitoring team that monitored and evaluated the Intensive Pulse Polio Immunization Program of the Ministry of Health, Government of India.

Other Relevant Experience

 

Utah Entrepreneurial Challenge, 2003, Marriott School of Business, University of Utah.
Finalist, placed in the top-ten out of 120 teams in this statewide event. The business plan, ‘Biosyndicates', dealt with automation of clinical trials and clinical research protocols.

Utah Entrepreneurial Challenge, 2002, Marriott School of Business, University of Utah.
Finalist, placed fourth out of 40 teams statewide. The Business plan, ‘Biosyn', proposed a standard for genomic and proteomic data, and interlingua between different data sources. 

Pregnancy Induced Hypertension Symposium, Stanley Medical College, 1998
Organized and conducted a medical school level symposium on "Pregnancy Induced Hypertension (PIH)" and presented a paper titled "Etiology of PIH."

Professional Memberships and Activities

 

Current member of AMIA, HIMSS and IAMI; voting member of HL7.
Member of the National Cadet Corps (Medical Unit), obtained B level certificate, 1994 to 1998.

References

 

Available on request.

           

 Last updated: November 22, 2009.

Senthil K. Nachimuthu

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Last Updated ( Sunday, 22 November 2009 )
 
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